非生物型人工肝与中药结肠透析优化治疗肝衰竭的临床研究

Clinical Research on Non-bioartificial Liver Combined with Traditional Chinese Medicine Colon Dialysis to Liver Failure

目的观察非生物型人工肝与中药结肠透析优化治疗肝衰竭的治疗效果.方法随机选取昆明市第三人民医院103例肝衰竭应用非生物型人工肝血浆置换与中药结肠透析优化治疗的患者和100例仅行人工肝浆置换术治疗的患者,进行临床疗效的比较分析.结果血浆置换联合中药结肠透析治疗对肝功能、凝血酶原活动度、细胞因子指标的改善优于单纯的血浆置换(P<0.05);同时,在减少人工肝治疗频次、血浆用量比较优于单纯的血浆置换(P<0.05),从而降低患者住院总费用(P<0.05),减轻患者经济负担.结论非生物型人工肝血浆置换与中药结肠透析优化治疗肝衰竭优于单独的人工肝治疗。

Objective Observe the therapeutic effect of non-bioartificial liver combined with traditional Chinese medicine colon dialysis to liver failure. Methods 103 patients were randomly selected with non-bioartificial liver and traditional Chinese medicine colon dialysis therapy, 100 patients with non-bioartificial liver therapy, and the therapeutic effect of two groups was analyzed and compared by SPSS. Results Nnon-bioartificial liver plasma- pheresis combined with traditional Chinese medicine colon dialysis were better than simple plasmapheresis in treating live failure, including improving liver function, prothrombin activity , cytokines, reducing the therapeutic frequency and dosage of plasmapheresis, and reducing the health care cost. Conclusion Non-bioartificial liver combined with traditional Chinese medicine colon dialysis is better than primary artificial liver in liver failure treatment