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CD4^＋T细胞表型转换及其调控机制的研究 被引量：2

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摘要 CD4^＋T细胞亚群在机体正常的免疫调节中发挥重要的作用.起初认为CD4^＋T细胞分为两大亚群,即分泌IFN-γ的Th1细胞和分泌IL-4的Th2细胞.其分别表达转录因子为T-bet和Gata-3.随后发现CD4^＋T细胞家族的新成员调节性T细胞,调节性T细胞表达转录因子为Foxp3和分泌TGF-β、IL-10.
作者 戴玉洁 于飞 胡绍先
机构地区 华中科技大学同济医学院附属同济医院风湿免疫科
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2015年第1期55-57,共3页 Chinese Journal of Rheumatology
关键词 CD4^+T细胞亚群 表型转换 调节性T细胞 调控 转录因子 T-BET TH2细胞 TH1细胞
分类号 R392 [医药卫生—免疫学]
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参考文献20

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同被引文献55

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中华风湿病学杂志
2015年 第1期

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