三维动态增强MRA与DSA诊断下肢动脉硬化闭塞症的对比研究

The Comparative Study of 3D CE-MRA with DSA in Lower Extremity Arteriosclerotic Obliterans

目的评价三维动态增强MRA(3D CE-MRA)诊断下肢动脉硬化闭塞症(ASO)的准确性及应用价值。方法通过3D CEMRA和DSA两种不同的影像学检查方法对ASO成像结果进行对比研究。结果与DSA相比较,3D CE-MRA评价ASO的符合率为90.5%;诊断下肢动脉病变的灵敏度为98.17%,特异度95.05%,准确率96.67%,阳性预测值95.54%,阴性预测值97.96%。结论对比研究结果表明:DSA仍是目前ASO诊断的"金标准",但其具有创伤性、风险较大且费用高,不适宜作为下肢狭窄的首选诊断方法。3D CE-MRA对全下肢血管病变显示有独特优势,具有无创、无辐射的特点,可作为ASO的主要检测手段。

Objective Evaluated 3D dynamic contrast-enhanced magnetic resonance angiography （3D CE-MRA） diagnosis accuracy and application of arteriosclerotic obliterans （ASO） of the lower limbs. Methods Adopted by the 3D CE-MRA and DSA, the two different image diagnosis methods,the image results of ASO were compa-ratively studied. Results Compared with the results of DSA. Lower limb artery stenosis valuation of 3D CE-MR coincide rate was 90.5%. For lower limb artery lesions diagnostic, the sensitivity, specificity, accuracy, positive pre-dictive value, and negtive predictive value of 3D CE-MRA were 98.17%, 95.05%, 96.67%, 95.54%, and 97.96%,respectively. Conclusion The compared results show that：DSA lower limb artery stenosis diagnosis was＂gold standard＂, but it was invasive, risk and cost. Not suitable for a Lower limb artery stenosis diagnostic first choice method. The 3D CE-MRA has unique advantages on exploring vascular lesions in lower limbs. It was also noninvasive, no radiation and simple that will become the main testing methods for ASO.