胃癌手术患者2338例临床病理特征分析

Analysis of clinicopathologic features of 2338 patients with gastric cancer underwent operation

目的分析2 338例胃癌手术患者的临床病理特征。方法回顾性分析2 338例胃癌患者的临床资料。患者分为年龄≤40岁(A组)、41-65岁(B组)和>65岁(C组)三组,比较肿瘤部位、病理类型和临床分期。结果胃癌高发年龄41-65岁,男性比例高于女性。肿瘤多见于贲门胃底部(42.48%)。肿瘤以BormannⅡ型多见(75.44%),病理类型以腺癌为主(90.03%)。肿瘤分化程度以低分化为主(74.25%)。胃癌浸润深度以T3期主(64.6%)。淋巴结转移以N0、N1期为主(85.31%)。TNM分期以Ⅲ期为主(48.47%)。结论胃癌高发于41-65岁男性。胃癌病理分型以低分化腺癌最常见。确诊患者多为胃癌中晚期,胃癌早期诊断率有待提高。

Objective To analyze the clinicopathologic features of 2 338 patients with gastric cancer underwent operation.Methods Clinical data of 2 338 patients with gastric cancer were retrospectively analyzed,who were assigned into three groups of A（≤40years old）,B（41-65 years old）and C（〉65years old）.Clinical features including tumor location,pathological type and clinical stage were compared among three groups.Results The morbidity of gastric cancer was the highest in group B,which was more in male than that in female.The tumors located mostly in the cardia and bottom of stomach（42.48%）with a type of Bormann Ⅱ（75.44%）.Pathologically,the tumors were diagnosed mostly as adenocarcinoma（90.03%）,low differentiation（74.25%）,and invasion depth in T3 stage（64.6%）,lymph node metastasis of N0 and N1 stags（85.31%）and TNM stage of Ⅲ（48.47%）.Conclusion High incidence rate of gastric cancer occurs in men aged from 41 to 65years old.Adenocarcinoma with low differentiation is the most commonly seen pathological type of gastric cancer.The patients confirmed as gastric cancer are usually diagnosed in middle-late phase.Early diagnosis of gastric cancer needs to be paid more attention to.