摘要
目的:探讨分析实质型多形性黄色星形细胞瘤(PXA)的临床、病理及影像学表现特征。方法:回顾性分析经病理证实的23例PXA患者的临床、病理及影像学资料,重点观察、分析11例实质型PXA的病变部位、病灶大小、瘤周水肿、恶变发生率及MRI信号特征。结果:11例实质型PXA患者中,发病平均年龄为(31.0±9.7)岁,9例(81.8%)病程≤1年;病变累及颞叶8例(72%),岛叶3例(27%),囊变发生率为72.7%(8/11);实质型PXA的瘤体体积中位数为7.2cm3;无水肿或轻度水肿3例(27%),中度水肿7例(64%),实质型PXA恶变发生率为9%(1/11)。实质型PXA MRI表现为实性肿块(伴或不伴囊变区),多数形态规则,边界清楚,实质部分T1WI呈等、低信号,T2WI呈高信号,瘤周水肿较轻,增强扫描呈明显较均匀或不均匀强化,邻近脑膜一侧强化显著。结论:实质型PXA的病程较短,肿瘤体积较小,恶性程度较低,MRI表现有一定的特征性,手术切除预后较好。
Objective:To study the clinical,pathological and MR imaging characteristics of solid type pleomorphic xanthoastrocytomas(PXA).Methods:The clinical and pathological materials of 23 cases with PXA were analyzed retrospectively,mainly concentrated on the location,size,peri-tumoral edema,incidence of malignant change as well as the MRI characteristics.Results:Of the 11 patients with solid type PAX,the mean age of onset was(32±9.7)y.The course of the illness in 9patients(81.8%)was less than one year.Tumor located in the temporal lobe(8cases,72.7%)and in insula(3cases,27%).Cystic degeneration were seen in 8cases(72.7%).The median of tumor volume was 7.2cm3.Peritumoral edema was absent or mild in 3patients(27%)and moderate in 7patients(64%).The incidence of malignancy of solid type PXA was 9%(1/11cases).MR imaging showed that most of the tumors were solid,with or without cystic area,mostly regular in shape,with well-defined boundaries.The solid components of tumors were isointense or hypointense on T1 WI,and hyperintese on T2 WI with heterogeneous enhancement after contrast administration.Marked adjacent leptomeningeal enhancement could be seen.Conclusion:Solid type PXA had a short course of illness;with small tumor size and low degree of malignancy,showing agood outcome after surgical excision.Certain MR imaging characteristics could be revealed.
出处
《放射学实践》
北大核心
2015年第1期21-24,共4页
Radiologic Practice
基金
广州市科技计划项目(2014J4100071)
关键词
星形细胞瘤
磁共振成像
病理学
Astrocytoma
Magnetic resonance imaging
Pathology