良、恶性胰腺导管内乳头状黏液性肿瘤CT特征与病理联系

Benign and Malignant Intraductal Papillary Mucinous Neoplasm of Pancreas:CT Features and Correlation with Pathological Findings

目的探讨良、恶性胰腺导管内乳头状黏液性肿瘤(P-IPMN)CT特征及其病理联系。方法搜集并分析在本院治疗的40例P-IPMN患者影像学及病理资料,所有患者都进行了CT平扫加增强检查,运用统计学方法分析良、恶性P-IPMN的病理学及影像学差异。结果良、恶性P-IPMN在性别、发病年龄、发病部位、有无慢性胰腺炎病史上无显著性差异(P>0.05);在病灶大小、胆总管扩张、壁结节大小、主胰管扩张程度、CA19-9是否升高上有显著性差异(P<0.05)。结论良、恶性P-IPMN的CT表现具有一定特征性,影像学检查能为临床医师术前判断其生物学特性提供重要参考。

Objective To investigate the CT imaging features of benign and malignant intraductal papillary mucinous neoplasm of pancreas （P-IPMN） and to discuss the correlation between imaging features and pathological findings. Meth- ods A total of 40 patients with P-IPMN, who were treated at authors＇ hospital, were enrolled in this study. Both plain and contrast-enhanced CT scans were performed in all patients, and the imaging materials and the pathological findings were reviewed. The results were statistically analyzed. Results No statistically significant differences in the sex, age of onset, lesion＇ s location, presence or absence of chronic pancreatitis history, etc. existed between the benign P-IPMN group and the malignant P-IPMN group （ P 〉 0.05 ）. The differences in the lesion＇ s size, dilatation of the common bile duct, mural nodule size, diameter of dilated main pancreatic duct and the elevation of CA19-9 level between the benign P- IPMN group and the malignant P-IPMN group were statistically significant （ P 〈 0.05 ）. Conclusion Both benign and ma- lignant intraductal papillary mucinous neoplasm of pancreas have certain CT features. Preoperative imaging examination can provide the clinical physicians with important information which is very helpful in judging its biological characteristics.