血液指标在脑梗死和冠心病鉴别诊断中的临床意义

Clinical Significance of Blood Index in the Differential Diagnosis of Cerebral Infarction and Coronary Heart Disease

目的:探讨血液指标在脑梗死和冠心病鉴别诊断中的临床意义。方法:选择在笔者所在医院就诊并住院治疗的冠心病患者100例(冠心病组)、脑梗死患者92例(脑梗死组)及健康体检者100例(健康体检组),比较冠心病组及脑梗死组患者的血小板参数及血液流变学指标,并与健康体检组作比较。结果:冠心病组平均血小板体积MPV(12.48±1.28)fl及大血小板比例P-LCR(46.80±33.73)%,脑梗死组血小板计数PLT(195±65.7)×109/L明显高于健康体检组;冠心病病组、脑梗死组高切全血黏度、低切全血黏度、红细胞压积比明显高于健康体检组,红细胞变形指数明显低于健康体检组(P<0.05或<0.01)。结论:定期检测血小板参数和血液流变学指标对预测心脑血管疾病的发生具有重要意义。

Objective：To investigate the clinical significance of blood index in the differential diagnosis of cerebral infarction and coronary heart disease. Method：100 patients with coronary heart disease hospitalized in our hospital（the coronary heart disease group）,92 patients with cerebral infarction patients（the cerebral infarction group） and 100 healthy peoples（the healthy group） were selected,index comparison of platelet parameters and blood rheology in patients with three groups.Result：The mean platelet volume（MPV） was （12.48±1.28）fl and large platelet ratio（P-LCR） was （46.80±33.73）% in the coronary heart disease group,platelet count（PLT） was （195.0±65.7）×109/L in the cerebral infarction group,was higher than that in the healthy group.High shear whole blood viscosity, low shear whole blood viscosity,hematocrit ratio was higher in the coronary heart disease group and cerebral infarction group than that in the healthy group, erythrocyte deformation index was significantly lower than that in the healthy group （P＆lt;0.05 or ＆lt;0.01）.Conclusion：The regular detection of platelet parameters and blood rheology index have important significance for predicting the occurrence of cardiovascular and cerebrovascular diseases.