袖状切除在中央型肺癌中的应用

Application Study of Sleeve Resection in Treating Central Type Lung Cancer

目的:研究袖状切除在中央型肺癌中的应用价值。方法:将58例中央型期肺癌患者,按手术术式分为观察组和对照组,各29例,观察组患者接受袖状切除术,对照组患者接受全肺切除术,比较两组患者的手术时间、术中出血量、拔除胸管时间、胸液引流量远期疗效以术后卧床时间、(3年和5年)生存率、复发率及肺功能改变。结果:观察组患者手术时间明显长于对照组,术中出血量、拔除胸管时间、胸液引流量、术后卧床时间均明显低于对照组,差异有统计学意义(P<0.05);两组患者3年和5年的生存率、复发率以及存活时间无差异(P>0.05);观察组1s用力呼气容积(FEV1)和用力肺活量(FVC)明显高于对照组,差异有统计学意义(P<0.05)。结论:袖状切除术有助于减小手术创伤,术后恢复快,能较好的保留患者的肺功能,且疗效与全肺切除术相当。

Objective： To study the application value of sleeve resection in treating central type lung cancer. Methods： Fifty-eight patients with central type lung cancer were selected and divided into ob- servation group and control group according to operation method adopted. Patients in observation group underwent sleeve resection, while those in control group underwent pneumonectomy. Duration of oper- ation, bleeding amount during operation, time of taking off chest tube, amount of thoracic fluid drain- age, long-term curative effect, time needed in bed, survival rate （3-year or 5-year） , relapse rate and pulmonary function were compared between the two groups. Results： The operation time of observation group was obviously longer than that of control group （P 〈 0.05 ）. The intraoperative bleeding volume, chest tube removal time, postoperative chest drainage volume, and postoperative bedding time of obser- vation group were significantly lower than those of control group （ P 〈 0.05 ）. There was no statistical difference in 3-year and 5-year survival rate and recurrence rate, and survival time between the 2 groups （ P 〉 0.05 ） ; FVC, and FEV of observation group were significantly higher than those of control group （ P 〈 0.05 ）. Conclusion： Sleeve resection is an ideal method in treating central type lung canc- er since it can reduce operation wound, promote postoperative recovery, maximize the reservation of lung function, and achieve equal long-term curative effect with pneumonectomy.