间充质干细胞源性微囊泡在关节软骨损伤修复中的应用
摘要
微囊泡（microvesicles,MVs）是机体细胞在生理和病理状态下释放的直径在30-1 000nm之间的微小囊泡[1]。1967年,Wolf在血液系统中发现并首次报道了MVs,当时仅被看作细胞活化或损伤的标志物。近年来,随着研究的深入,MVs的损伤修复功能逐渐引起了人们的重视。
出处
《实用骨科杂志》
2015年第1期59-61,共3页
Journal of Practical Orthopaedics
基金
国家自然科学基金项目(81472091)
参考文献27
-
1Ratajczak J, Wysoczynski M, Hayek F^et al. Membrane-derived micro-vesicles : Important and underappreciatedmediators of cell-to-cell communication [ J ]. Leukemia,2006,20(9) :1487-1495.
-
2Cucci E,Racchetti G,Meldolesi J. Shedding microvesi-cles : artefaces no more [ J ]. Trends Cell Biol,2009,19(2):43-51.
-
3Mathivanan S,Ji H, Simpson R, ei al. Exosomes; extra-cellular organelles important in intercellular communi-cation [J] . Proteomics,2010,73 ( 10) : 1907-1920.
-
4Bruno S,Grange C,Deregibus MC, et al. Mesenchymalstem cell-derived microvesicles protect against acute tu-bular injury [ J ] . J Am Soc Nephrol,2009,20 ( 5 ):1053-1067.
-
5Gatti S,Bruno S,Deregibus MC,et al. Microvesicles de-rived from human adult mesenchymal stem cells protectagainst ischaemia-reperfusion-induced acute and chron-ic kidney injury [ J ] . Nephrol Dial Transpl, 2011,26. (5):1474-1483.
-
6Bruno S, Grange C, Collino F, et al. Microvesicles de-rived from mesenchymal stem cells enhance survival ina lethal model of acute kidney injury [ J ]. PLoS One,2012,7(3) :e33115.
-
7He J, Wang Y,Sun S,ef al. Bone Marrow stem cells-de-rived micro-vesicles protect against renal injury in themouse remnant kidney model [ J ]. Nephrology ( Carl-ton) ,2012,17(5) :493-500.
-
8Herrera MB,Fonsato V,Gatti S,ef al. Human liver stemcell-derived microvesicles accelerate hepatic regenera-tion in hepatectomized rats [ J ]. J Cell Mol Med,2010,14(6B) :1605-1618.
-
9Zhu YG, Feng XM, Abbott J, et al. Human Mesenchy-mal Stem Cell Microvesicles for Treatment of E. coliEndotoxin-Induced Acute Lung Injury in Mice[ J]. StemCells,2014,32(1) :116-125.
-
10Zhang HC, Liu XB, Huang S, et al. Microvesicles de-rived from human umbilical cord mesenchymal stemcells stimulated by hypoxia promote angiogenesis bothin vitro and in vivo[ J] . Stem Cells Dev,2012,21 ( 18):3289-3297.
二级参考文献33
-
1Conde-Vaneells J, Rodriguez-Suarez E, Embade N, et al. Character- ization and comprehensive proteome profiling of exosomes secreted by hepatocytes [ J ]. J Proteome Res,2008,7 ( 12 ) :5157-5166.
-
2Thery C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses[J]. Nat Rev I mmunol,2009,9(8) :581-593.
-
3Cocucci E, Racchetti G, Meldolesi J. Shedding microvesicles : arte- facts no more[J]. Trends Cell Biol,2009,19(2) :43-51.
-
4Lai RC, Arslan F, Lee MM, et al. Exosome secreted by MSC re- [ 291 duces myocardial ischemia/reperfusion injury[ J]. Stem Cell Res, 2010,4(3) :214-222.
-
5Sahoo S, Klychko E, Thome T, et al. Exosomes from human CD34 T stem cells mediate their proangiogenic paracrine activity [ J ]. Circ Res, 2011,109 ( 7 ) : 724 -728.
-
6Wolf P. The naiure-and signifiance of platelet products in human nlasma[J]. Br .1 Haematol. 1967.13 ( 3 ) ,269-288.
-
7Freyssinet JM. Cellular microparticles: what are they bad or good for? [J]. J Thromb Haemost,2003,1 (7) :1655-1662.
-
8Jimenez J J, Jy W, Mauro LM,et al. Endothelial cells release pheno- typically and quantitatively distinct microparticles in activation and apoptosis [ J]. Thromb Res ,2003,109 (4) : 175-180.
-
9Deregibus MC, Cantaluppi V, Calogero R, et al. Endothelial pro- genitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA [ J ]. Blood, 2007,110 ( 7 ) : 2440-2448.
-
10Aliotta JM, Sanchez-Guijo FM, Dooner GJ, et al. Alteration of mar- row cell gene expression, protein production, and engraftment intolung by lung-derived microvesicles: a novel mechanism for pheno- type modulation[ J]. Stem Cells,2007,25(9) :2245-2256.
共引文献3
-
1虞宇楠,宋浩明.微囊泡与急性冠脉综合征关系的研究进展[J].国际心血管病杂志,2014,41(5):300-303.
-
2侯威宇,程艳伟,向川.间充质干细胞源性微囊泡和诱导性多潜能干细胞促进关节软骨修复的进展[J].中国组织工程研究,2015,19(41):6706-6710. 被引量：3
-
3陈文杰,汪建样,殷明,殷嫦嫦.人脐带间充质干细胞抗肿瘤机制的研究进展[J].中国生物工程杂志,2017,37(3):78-82. 被引量：2
-
1吴明忠,周建胜.腹部脏器外淋巴管瘤的CT诊断[J].放射学实践,2007,22(10):1073-1076. 被引量：2
-
2曾辉.示教片[J].影像诊断与介入放射学,2008,17(1).
-
3欧阳学农.别让胸透成“凶”透[J].养生保健指南（中老年健康）,2013(5):53-54.
-
4周泽林.胸透致癌真假辨[J].东方药膳,2014(5):63-64.
-
5袁绍华,刘志弢.干细胞治疗急性放射病的研究进展[J].中南医学科学杂志,2013,41(6):602-604.
-
6王明辉,张斌,陈虎.间充质干细胞治疗急性放射损伤的研究进展[J].中华放射医学与防护杂志,2015,35(7):555-558. 被引量：3
-
7李康印,刘无非,敖国昆,魏若林,胡丽彩.药物微囊对原发性肝癌肝动脉栓塞的实验及临床观察[J].西北国防医学杂志,1991,12(2):3-4.
-
8朱寿彭,杨占山,赖冠华.SOD对小鼠内污染^（147）Pm损伤机体细胞的防护作用[J].辐射防护,1995,15(4):302-306. 被引量：1
-
9汪国余,谭恺,黄抒佳,徐祖良.儿童骶尾部卵黄囊瘤的影像学表现（附2例报告及文献复习）[J].实用放射学杂志,2010,26(12):1843-1844. 被引量：4
-
10冯敏,王吉侯,郭红平.自动痔疮套扎术联合外切治疗混合痔的临床观察[J].中国肛肠病杂志,2016,0(9):33-34. 被引量：3
