檵木叶的化学成分研究

Chemical Constituents from Leaves of Loropetalum chinense

目的研究檵木叶的化学成分。方法药材采用丙酮提取，利用大孔树脂柱、ODS反相柱、硅胶柱、Sephadex LH-20等色谱技术进行提取分离，根据波谱数据对化合物进行结构鉴定。结果从檵木叶中分离得到11个化合物，分别鉴定为β-D—glucopranosyl（Z）-3-hexenol（1）、ampelopsisionoside（2）、红景天苷（3）、2-hydroxy-5-[3-hydroxybutyl]phenyl-β-D—glucopyranoside（4）、杨梅素-3—O-α-L-鼠李糖苷（5）、6″-O-galloylsalidroside（6）、绿原酸甲酯（7）、绿原酸（8）、杨梅素-3-O-β-D-葡萄糖苷（9）、angionoside—A（10）、benzyl—α-L—rhamonopyranosyl-（1→6）-β—D—glucopyranoside（11）。结论化合物1～4、6、10、11为首次从该属植物中分离得到。

OBJECTIVE To study the chemical constituents of Loropetalum chinense leaves. METHODS The acetone extract was isolated and purified by macroporous resin, ODS column, silica gel column and Sephadex LH - 20 chromatography. All compounds were identified on the basis of spectral analysis. RESULTS Eleven compounds were isolated from Loropetalum chinense leaves and identified as β-D-glucopranosyl （Z） -3-hexenol （ 1 ）, ampelopsisionoside （ 2 ）, salidroside （ 3 ）, 2 -hydroxy-5- [ 3-hydroxybutyl ] phenyl-β- D-glueopyranoside（ 4 ）, myricetin 3-O-ct-L-rhamnoside （ 5 ）, 6″-O-galloylsalidroside （ 6 ）, methyl chlorogenate （ 7 ）, chlorogenic acid （8）, myricetin-3-O-β-D-glucoside（9）, alangionoside-A（10）, and benzyl-α-L-rhamonopyranosyl-（1→6） -β-D-glucopyranoside（ 11）. CONCLUSION Compounds 1 -4, 6, 10 and 11 are isolated from this genus for the first time.