超多孔水凝胶体系的溶胀和溶蚀动力学研究

Swelling and erosion kinetics of superporous hydrogel

目的考察含魔芋葡甘聚糖的超多孔水凝胶复合物在介质中溶胀和溶蚀动力学特点及其影响因素。方法采用泡沫聚合法制备超多孔水凝胶和加入魔芋葡甘聚糖的超多孔水凝胶,测定它们在介质p H、酶、Na Cl和葡萄糖作用下体系溶胀比和随时间变化的溶蚀率。结果魔芋葡甘聚糖-超多孔水凝胶复合物在蒸馏水中溶胀和溶蚀均最快,3 min溶胀比为161.3,48 h溶蚀率为85.6%,而超多孔水凝胶达到溶胀平衡较慢;魔芋葡甘聚糖-超多孔水凝胶复合物在含Na Cl或葡萄糖介质中溶胀和溶蚀减弱,其中Na Cl的影响比葡萄糖显著;与不含酶的介质(不同p H)相比,酶的存在加快了魔芋葡甘聚糖-超多孔水凝胶复合物体系的溶蚀。结论魔芋葡甘聚糖加入后所形成的超多孔水凝胶复合物体系溶胀性能较优而溶蚀延缓,但介质p H、酶、盐和糖等因素会影响体系溶胀和溶蚀行为。

AIM To study the swelling and erosion kinetics of superporous hydrogel composite containing Konjac glucomannan in different media.METHODS Superporous hydrogels with or without Konjac glucomannan were prepared by foam polymerization method.Their swelling and erosion ratios of Konjac glucomannan-superporous hydrogel composite were tested in dissolution media with varied pH values,enzyme,Na Cl and glucose.RESULTS Konjac glucomannan-superporous hydrogel composite reached a fast swelling ratio of 161 in 3 min,and erosion ratio of 85.6% in distilled water in 48h; but the behavior was relatively slow once there existed a swelling equilibrium.The swelling and erosion processes of Konjac glucomannan-superporous hydrogel were retarded by Na Cl or glucose,and such influence by Na Cl was more significant than that of glucose.The enzyme could increase more the erosion of Konjac glucomannan-superporous hydrogel as compared to an environment containing no enzyme.CONCLUSION The superporous hydrogel system can be endowed with good swelling and slow erosion performance by the addition of Konjac glucomannan.But pH adjusting agents,enzyme,Na Cl or glucose can significantly influence the swelling and erosion kinetics of Konjac glucomannan-superporous hydrogel composite.