植物源脂肪酶抑制剂研究进展

Review on Pancreatic Lipase Inhibitors Derived from Plants

脂肪酶抑制剂通过抑制脂肪酶的活性,减少食物中脂类物质的消化和吸收,达到控制和治疗肥胖的目的。植物来源的天然产物化合物具有来源广泛、结构多样、特异性高、毒性低等特点,因而从植物中筛选安全有效的脂肪酶抑制剂成为研究热点。本文综述了脂肪酶活性测定方法以及植物来源的不同结构类型的脂肪酶抑制剂研究进展。

Lipase inhibitors can reduce the digestion and absorption of dietary lipids by inhibiting pancreatic lipase activ- ity,achieving the purpose of the eontrel and treatment of obesity. Plant-derived natural products have a lot of virtues, such as a wide range of soumes, structural diversity, highly specificity and low toxicity. Therefore, sereening of safe and effective/ipase inhibitors derived from plant become a hot topic. This paper reviewed beth the methods of determination of lipase inhibiting activity and the lipase inhibitors derived from plants based on the chemical structure.