我院415例患者注射用脑蛋白水解物应用分析

Analysis of the Utilization of Cerebroprotein Hydrolysate for Injection in 415 Cases of Our Hospital

目的:为临床合理使用注射用脑蛋白水解物提供参考。方法:调取我院2014年1-4月使用注射用脑蛋白水解物部份病历,参照药品说明书、专著、临床诊疗指南,就其应用适应证、用法用量、溶剂选用、配置浓度、用药时间、用药禁忌等内容进行回顾性统计、分析,讨论其用药合理性。结果:共收集415例患者信息,有112例病例存在用药不合理情况,占26.99%。其中无指征用药47例,占11.33%;溶剂选择不合理72例,占17.35%;配置浓度不当2例,占0.48%;存在用药禁忌1例,占0.24%;疗程不当17例,占4.10%。病例中同时存在两项不合理的有27例,占6.5%。结论:临床应用注射用脑蛋白水解物存在不合理现象,提示医务人员需充分掌握该药适应证,严格按照药品说明书规范使用,建立可持续改进的辅助用药管理体系,以促进临床安全、合理、经济用药。

OBJECTIVE： To provide reference for ratioral use of cerobroprotein hydrolysate for injection in the clinic. METH- ODS： The cases of Cerebroprotein hydrolysate for injection were collected from our hospital during Jan.-Apr. 2014, and then analyzed retrospectively in terms of indications, usage and dosage, the selection of solvent, the concentration of configuration, drug use time, taboo and so on according to drug package inserts, treatise and clinical treatment guide. The rationality of drug use was discussed. RESULTS： Among 415 cases, there were 112 cases of irrational drug use, accounting for 26.99 %. There were 47 cases of nonindicated use of drugs （ 11.33 % ）, 72 cases of irrational solvent selection （ 17.35 % ）, 2 cases of improper configuration concentration （0.48 % ）, 1 case of taboo （0.24%）, 17 cases of improper treatment period （4.10%）. Among them, 2 items of irrational data existed in 27 cases, accounting for 6.5 %. CONCLUSIONS： The clinical application of Cerebroprotein hydrolysate for injection existed unreasonable phenomenon, thus it＇ s remind the medical staff should know the drug indications very well, use drug strictly according to the instructions, establish adjuvant management system with sustainable improvements, so as to promote the clinical safety, rational and economic use of dru~.