我院190例药品不良反应报告分析

Analysis of 190 Cases of ADR Reports in Our Hospital

目的:了解我院药品不良反应(ADR)发生的特点及规律,为临床合理用药提供参考。方法:采用回顾性分析方法,对我院2013年1-12月收集的190例ADR报告进行统计、分析。结果:190例ADR报告中,由抗感染药引起的ADR居首位(占50.52%),其次为中药制剂(占14.06%);ADR临床表现以皮肤及其附件损害最为常见,占56.07%;190例ADR报告中,有5例严重的ADR;ADR病例中有174例治愈,16例好转。结论:加强ADR的监测和报告有利于减少或避免ADR的重复发生。

OBJECTIVE： To analyze the characteristics of ADR in our hospital and promote clinical rational use of drug. METHODS： With the retrospective analysis method, a total of 190 ADR cases in our hospital from Jan. to Dec. 2013 were statistically analyzed. RESULTS： Among the total 190 cases, the top one was caused by anti-infective drugs, accounting for 50.52%, followed by TCM preparation, accounting for 14.06%. The most common manifestation was lesion of skin and its appendents, accounting for 56.07%. There were 5 serious ADR cases among the 190 ADR cases. There were less new and serious ADR reports in our hospital, 174 cases were cured, 16 cases were taking aturn for the better. CONCLUSIONS： Great importance should be attached to ADR propaganda, ADR monitoring and reporting, and rational use of drug to reduce or avoid ADR.