自发性冠状动脉夹层的研究进展

Progress in Research of Spontaneous Coronary Artery Dissection

自发性冠状动脉夹层为一种少见的可导致急性冠状动脉综合征,甚至猝死的冠状动脉疾病。其主要表现为冠状动脉内膜自发撕裂或冠状动脉壁内滋养血管出血形成血管夹层,影响正常冠状动脉血液供应。与冠状动脉粥样硬化、围产期女性体内激素水平改变、动脉壁中层结构变异等因素相关。近年来随着诊断手段的提高及介入技术的广泛应用,病死率有所下降,现对近年研究进展做一综述。

Spontaneous coronary artery dissection（ SCAD） is a rare cause of acute coronary syndrome and sudden death. The main manifestation of SCAD is spontaneous coronary artery intimal tear or bleeding in the nutrient vessel,affecting the normal coronary blood supply.SCAD is related to coronary atherosclerosis,perinatal female hormone level changes,and arterial wall structural variation. In recent years,improvements in diagnosis of SCAD combined with the use of extensive interventional techniques,means that the fatality rate has decreased.