门头沟区宫颈癌筛查302例宫颈不典型鳞状上皮病变结果分析

目的总结门头沟地区妇女宫颈癌筛查宫颈不典型鳞状上皮病变的发生率与年龄的关系,并分析阴道镜检查下的病理结果。方法回顾性分析35~59岁行宫颈癌筛查巴氏涂片结果 ASCUS的妇女,在阴道镜定位下多点活检的组织病理学检查。结果 302例宫颈细胞学诊断为ASCUS患者,45~49岁年龄组宫颈上皮内瘤变CINII^III的发生率(25.53%)高于其他年龄组,差异有统计学意义(P<0.05)。40~44岁年龄组CINII^III的发生率(16.67%)高于35~39组、50~54组、55~59组CINII^III的发生率,差异有统计学意义(P<0.05)。302例ASCUS患者中,阴道镜诊断的≥LSIL119例(39.40%),阴道镜指导下组织活检,病理学诊断109例(36.09%),病理学和阴道镜诊断阳性符合率为91.59%。结论 40~49岁ASCUS患者直接做阴道镜引导下多点取活检,其他年龄组ASCUS患者阴道镜检查若未发现病变,6个月后复查细胞学检查;阴道镜检查以及阴道镜下取活检对ASCUS的处理具有较高的临床价值。

Objective To discuss the relationship between Atypical Squamous Cells of Undetermined Significance （ASCUS） incidence and age of cervical cancer screening, analyze the results of pathological in colposcopy in Mentougou district. Methods Retrospective analysis 35-59 years old women cervical cancer screening Pap smear results ASCUS of histological pathology of multiple biopsy under colposcopy examination in positioning from January 2011 to December 2012 in Mentougou District. Results 302 cases of cervical cytological diagnosis of patients, the incidence of 45- 49 years old age group cervical intraepithelial neoplasia （CIN） I1-111（25.53%） was higher than other age groups, the difference was statistically significant （P〈0.05） .The incidence of CIN 11-111 in 40-44 years old age group CIN II-III （16.67%） was higher than that in 35-39 years old age group, 50-54 group, 55-59 group, the difference was statistically significant （P〈0.05） .302 patients with ASCUS,colposcopy in the diagnosis of ≥ LSIL in 119 cases （39.40%）, colposcopy guided biopsy, pathological diagnosis of 109 cases （36.09%）, pathology and colposcopy diagnosis coincidence rate was 91.59%.Conclusion The ASCUS patients in 40-49 years old do colposcopy guided multipoint biopsy, other age group ASCUS patients if not found lesions in colposcopy, need the cytology after 6 months; there have great clinical value of colposcopy and biopsy under colposcope on ASCUS.