自血穴位注射疗法联合氯雷他定治疗ASST阳性的慢性荨麻疹120例疗效观察

Clinical effect of autohemotherapy combined loratadine on 120 cases of ASST positive chronic idiopathic urticaria

目的探讨自血穴位注射疗法治疗自身血清皮肤试验(ASST)阳性的慢性荨麻疹的疗效及安全性。方法将2012年4月至2013年1月在该科就诊的120例慢性荨麻疹患者分为观察组和对照组,每组60例。观察组每天口服氯雷他定,每次10mg,并辅以自血穴位注射疗法;对照组单用氯雷他定,方法同观察组。疗程均为12周,观察两组治疗对慢性荨麻疹的有效率及安全性。结果观察组和对照组的有效率分别68.33%和48.33%,两组比较差异有统计学意义(P<0.01)。结论自血穴位注射疗法联合氯雷他啶治疗ASST阳性的慢性荨麻疹有效率高,安全性好,其远期疗效有待进一步观察。

Objective To investigate the efficacy and safety of autohemotherapy therapy in ASST positive chronic idiopathic urticaria.Methods One hundred and twenty cases of chronic idiopathic urticaria treated in our department from April,2012 to January,2013 were divided into treatment group and control group,60 cases in each group.Patients in treatment group were given oral ioratadine（10mg/d）,supplemented by autohemotherapy;patients in control group were only given oral ioratadine（10mg/d）.Both of the two groups were treated with twelve weeks,then observed the effectiveness and safety of two kinds of treatment.ResultsThe effective rate of treatment group and control group were 68.33%and 48.33%respectively,and there was significant difference between the two groups（P〈0.01）.Conclusion Autohemotherapy combined antihistamine was of high efficiency and safety in the treatment of ASST positive chronic idiopathic urticaria,while the lonG^-term curative effect remains to be observed.