探讨氟马西尼对丙泊酚残余麻醉作用的拮抗作用

A Discussion of the Resistant Effect of Flumazenil to the Lingering Anesthetic Action of Propofol

目的探讨氟马西尼能否加速丙泊酚麻醉后清醒过程。方法选取2012年9月-2013年12月牡丹江医学院第二附属医院80例使用丙泊酚进行麻醉的手术患者进行研究,随机分为观察组和对照组,观察组患者术后注射氟马西尼0.3mg,对照组未行特殊处理,观察2组患者清醒时间。结果观察组患者的反应性、语音、表情、眼睛镇静/警觉评分达到4分的时间均短于对照组,差异有统计学意义(P<0.05)。结论氟马西尼可加速丙泊酚麻醉后清醒过程。

Objective To discuss whether Flumazenil can shorten the wakening process after the anesthetization with Propofol. Method To select 80 cases of patients who have undergone anesthetized operations with Propofol at the Second Affiliated Hospital of Mudanjiang Medical School from September 2012 to December 2013 and divide them into the observation group and comparison group at random. The patients of the former were injected 0.3 mg Flumazenil after operations, while those of the latter received no special treatment, and to observe their respective wakening process. Results In terms of scores on reaction, verbal sound, facial expression, and ocular calmness/alertness reaching 4 points, the time required for the patients of the observation group was all shorter than that of the comparison group, and the differences were statistically significant （P〈 0.05）. Conclusion Flumazenil can shorten the wakening process after the anesthetization with Propofol.