摘要
目的 :了解基层社区卫生服务中心儿科门诊超说明书用药情况,为儿童合理用药提供依据。方法 :抽取1家社区卫生服务中心儿科门诊2个月的用药处方,根据药品说明书判断是否存在超说明书用药,对超说明书用药进行统计分析。结果 :共抽取处方678张,超说明书用药218张,发生率为32.15%。在218张超说明书用药处方中,共有超说明书用药283例,其中超剂量、超疗程为最常见的类型,构成比接近90.00%;超适应证用药、超适应人群用药和超给药途径用药构成比为11.66%。结论 :社区卫生服务中心儿科门诊用药存在超说明书用药现象,应对儿童用药进行密切监测。
Objective: To investigate the situation of the off-label drug use in the outpatient pediatric department of the community health service center so as to provide a reference for the rational drug use of children. Methods: The prescriptions of the outpatient pediatric department of one community health service center in 2 months were collected. Whether the offlabel drug use existed was evaluated according to the drug package inserts and statistically analyzed thereafter. Results: In 678 prescriptions totally selected, 218 were judged as the off-label drug use and its occurrence rate was 32.15%. In 218 prescriptions of off-label drug use, 283 cases were involved and among them the over dosage, and over course of treatment were the most common types, whose constituent ratio was close to 90%. The over indication of off-label drug use, over the target population and over administration route of the off-label drug use accounted for 11.66%. Conclusion: The phenomenon of the off-label drug use exists in the outpatient pediatric department in the community health service center and the medication for children should be closely monitored.
出处
《上海医药》
CAS
2015年第2期24-26,共3页
Shanghai Medical & Pharmaceutical Journal
关键词
儿科
门诊
超说明书用药
pediatric department
out-patient
off-label drug use