艾司洛尔防治瑞芬太尼麻醉后痛觉过敏的疗效

Esmolol control remifentanil anesthesia efficacy of hyperalgesia

目的：观察艾司洛尔术中持续输注对防治瑞芬太尼引起术后痛觉过敏的疗效。方法：选取60例腹腔镜胆囊手术患者,美国麻醉医师协会（ASA）分级Ⅰ-Ⅱ级,随机分为A组（瑞芬太尼）、B组（瑞芬太尼＋艾司洛尔）,每组各30例,B组手术中持续输注艾司洛尔（5-15μg/kg/min）,根据循环变化调整剂量,术前指导患者掌握疼痛视觉模拟评分（VAS评分）。记录患者术前、苏醒即刻、苏醒后30分钟的VAS评分。结果：苏醒即刻,两组VAS评分均较术前显著增加（P〈0.05）;B组与A组同时点对比,B组显著低于A组（P〈0.01）。结论：术中持续输注艾司洛尔能缓解瑞芬太尼引起的术后痛觉过敏。

Objective Observation of esmolol on the prevention and treatment of intraoperative continuous infusion of remifentanil cause efficacy of postoperative hyperalgesltr Method 60 cases of laparoscopic gallbladder surgery were selected, American Socie of Anesthesiologists （ASA） gradeⅠ-Ⅱ grade,they were randomly divided into A group （remifentanil） ,B group （remifentanil ＋ esmolol） ,30 patients in each group,B group surgery,continuous infusion of esmolol （5 - 15μg/kg/min） ,dose adjustments according to changes in circulation, control pain in patients with preoperative guidance of visual analogue scale （VAS score）. Records of patients before,wake up immediately, and awakens in the VAS score after 30 minutes. Results The Awakening immediate, the VAS score was increased significantly than those in the two groups preoperative （ P 〈 0. 05 ） ; B group at the same time point compared with the A group, B group was significantly lower than the A group （P 〈 0.01 ）. Conclusion The intraoperative continuous infusion of remifentanil and esmolol can ease postoperative pain caused by allergies.