免费孕前优生健康检查对降低出生缺陷的影响

The impact of free progestation eugenics health check on reducing the occurrence of birth defect

目的探讨免费孕前优生健康检查对降低新生儿出生缺陷的影响。方法选取章丘市农村不同地区2012年6月至2013年6月达到生育政策标准的9 000对计划内怀孕夫妇,按照是否参与了免费孕前优生健康检查分为检查组和未检查组,每组选取4 500对夫妇。对两组新生儿出生缺陷情况进行调查比较。结果检查组出生缺陷发生率为2.22‰(10/4 500),显著低于未检查组的12.22‰(55/4 500)(P﹤0.05)。排在前四位的出生缺陷依次为神经管畸形20例(2.22‰)、指(趾)畸形16例(1.78‰)、唇腭裂13例(1.44‰)、先天性心脏病9例(1.00‰)。结论孕前优生健康检查可有效降低出生缺陷发生率。

Objective To investigate the impact of free progestation eugenics health check on the occurrence of birth defect. Methods In the rural areas of Zhangqiu city, 9 000 rural couples who were qualified the childbearing policy between June 2012 and June 2013 were selected. All cases were divided into examination group and non - examination group according to whether participated free progestation eugenics health check, with 4 500 couples in each group. The occurrence of birth defect in two groups were compared. Results 10 cases with birth defect in examination group and 55 cases were in non - examination group. The birth defect rate of examination group was lower than that of non - examination group, the difference had statistical significance （ P 〈 0.05 ）. The top four birth defects were neural tube defects 20 cases （2. 22‰） , finger/toe malformation 16 cases （1.78‰） , cleft lip/palate 13 cases（1.44‰） and congenital heart disease 9 cases （1.00‰）. Conclusion The free progestation eugenics health check can decrease birth defect rate effectively.