儿科轮状病毒感染163例特征分析

Characteristics analysis of pediatric rotavirus infection in 163 cases

目的：研究重庆医科大学附属儿童医院婴幼儿轮状病毒（RV ）感染的流行特征，为RV腹泻的预防和控制提供基础资料。方法本课题采用胶体金法对320例腹泻患儿进行RV抗原检测，并对结果进行统计分析。结果检出RV抗原阳性163例，其中男108例，女55例，总检出率为50．93％。来自农村的患儿RV抗原阳性率最高，为62．03％，几乎是市区的2倍。发病高峰期为每年10月至次年2月，以1月最高，阳性率达到65．31％，有明显季节性。患儿发病年龄集中在2岁以内，其中以6～12个月RV阳性检出率最高，为63．36％。结论 RV是婴幼儿腹泻的主要病原体，胶体金法检测RV具有简单、快速、特异性高的特点，适合在各级医疗单位尤其是基层单位推广应用。

Objective To explore the epidemic characteristics of the rotavirus （RV ） infection in infants and young children in order to provide the basic data for the prevention and control of RV diarrhea. Methods The RV antigen was detected in 320 cases of children with diarrhea ,using collaurum method ,and the statistical analysis was carried out for analyzing the results. Results We detected 163 cases were positive ,in which 108 cases were male ,55 cases were female ,the total positive rate was 50. 93%. The positive rate of RV antigen in rural areas was the highest , reaching 62. 03% ,which was twice times than that in the city. The peak incidence was from October each year to February of the following year. The highest positive rate was 65. 31% ,which was in January ,showing a significant seasonal. Age concentrated in under 2 years old ,of which 6-12 months infants was the highest ,reaching 63. 36%. Conclusion The RV is the main pathogen of infant diarrhea. Colloidal gold method to detect the RV has the charac‐teristics of simple ,rapid ,high specificity ,suitable for application in the medical units at all levels ,especially the grass‐roots unit.