祛痰逐瘀法治疗血管性痴呆临床研究

Clinical Research of Eliminating Phlegm and Blood Stasis Method in the Treatment of Vascular Dementia

目的：观察祛痰逐瘀法治疗血管性痴呆的临床疗效。方法：将110例血管性痴呆患者随机分为治疗组与对照组,对照组静脉滴注吡拉西坦注射液与银杏叶注射液,治疗组在对照组基础上加用祛痰逐瘀方药,3周为1个疗程,治疗3～4个疗程。观察两组治疗前后简明精神状态检查（minimum mental stateexamination,MMSE）评分、日常生活活动能力量表（activities of daily livingscale,ADL）评分和临床痴呆评定量表（clinical dementia rating,CDR）的评分情况。结果：治疗后两组患者MMSE评分、ADL评分、CDR评分均较治疗前有所改善,且治疗组优于对照组（P〈0.01）;治疗组有效率81.0%,对照组61.5%,两组比较,差异有统计学意义（P〈0.01）。结论：祛痰逐瘀法治疗血管性痴呆临床疗效显著。

Objective： To observe the clinical curative effect of eliminating phlegm and blood stasis method in the treatment of vascular dementia. Methods： 110 patients with vascular dementia were randomly divided into treatment group and control group. The control group was given intravenous drip Piracetam injection and Yinxingye injection. On the basis of control group,the treatment group was given eliminating phlegm and hlood stasis prescription. and 3 weeks for a period of treatment,for 3-4 courses of treatment. Observed the concise mental state examination（ MMSE） score,daily life activities ability scale（ ADL） score and clinical dementia rating scale score（ CDR） of two groups before and after treatment. Results： Compared with before,the MMSE score,ADL scores,CDR grade of the two groups were improved. The effective rate was 81. 0% in treatment group and 61. 5% in control group. Compared of two groups,the difference was statistically significant（ P〈0. 01）. Conclusion： Eliminating phlegm and blood stasis method in the treatment of vascular dementia has distinct clinical curative effect.