260例妇科围手术期抗生素应用分析

Analysis on Antibiotics Application in Gynecological Perioperative Period of 260 Patients

目的分析我院在妇科围手术期抗生素的应用情况,研究存在的问题,探讨并制定合理的解决方案。方法以我院2013年1月开展实施的妇科围手术期抗生素干预为研究分界点,随机抽取干预前后各1年的妇科手术患者病历资料(其中2012年为"干预前",2013年为"干预后",两组均抽取130例),遴选12项评估指标对比干预前后的组间差异。结果 1干预前后患者年龄、手术切口类别差异无统计学意义,基线资料具有可比性;2干预后住院天数由干预前6.4天下降到5.3天,术后住院天数由干预前4.3天下降到3.9天,差异有统计学意义;3干预后术前抗生素使用时间、术后抗生素停用时间较干预前均降低,差异有统计学意义;4抗生素使用合理性5项指标均提高,整体合理性性由干预前的69.4%提高到88.6%。结论围手术抗生素使用普遍,需要进行合理的干预,以减轻患者负担,更好的保障患者利益,同时促进医疗诊疗行为的规范,降低医院管理风险。

Objective This study was aimed to analyze the application of antibiotics into our gynecological patients in perioperative period,and to research existing issues,discuss and make reasonable solution.Methods The perioperative period in January 2013 intervention of antibiotics applied into our gynecological patients was as the demarcation point of the research,then we randomly drew medical records of gynecological patients within one year respectively before and after the intervention（2012is classified as＂before intervention＂,and 2013as＂after intervention＂;130patients were drawn from two groups respectively）.And 12 evaluation indicators were selected to make a comparison of differences before and after the intervention.Results 1 There was no statistical significance for patients in age and category of surgical incision before and after the intervention.The baseline information had comparability;2 After the intervention,the hospital stay decreased from 6.4days before the intervention to 5.3days after the intervention.The hospital stay decreased from 4.3days before the intervention to 4.3days after the operation.The difference had statistical significance;3 After the intervention,both antibiotic use time before the operation and antibiotic outage time after the operation decreased,compared with that before the intervention.The different had statistical significance;4 Rationality of antibiotic use and another four indicators were all improved.Overall rationality was increased from 69.4% before in intervention to 88.6% after the intervention.Conclusion Antibiotics were universally used in perioperative period.It is necessary for reasonable intervention,so as to relieve burdens of patients,provide better guarantee to patients’ interests,promote the standardization of medical treatment and diagnosis behaviors,and reduce management risks of the hospital.