北京地区24家医院住院冠心病患者静息心率控制状况的调查

An epidemiologic study on resting heart rate status of hospitalized patients with coronary artery disease in 24 hospitals in Beijing

目的 调查住院冠心病患者静息心率达标状况、β-受体阻滞剂使用状况及安全性。方法 采用开放、多中心的观察性研究,连续入组北京24家医院2012年6月~2012年9月的住院冠心病患者,总计1570例。记录入、出院时患者的静息心率及β-受体阻滞剂的状况（种类、频率、剂量）。结果 出院时冠心病患者静息心率达标率为35.9%,入、出院静息心率为（71.00±13.61）bpm vs（65.27±9.96）bpm（P〈0.01）,β-受体阻滞剂使用率为80.06%vs 81.02%（P=0.16）,美托洛尔使用率为60.38%vs 60.70%（P=0.41）,入、出院酒石酸美托洛尔平均剂量为（29.55±24.6）mg/d vs（16.38±27.5）mg/d。结论北京市部分医院住院冠心病患者静息心率达标率不高,β-受体阻滞剂使用率及使用剂量均较低。

Objective To explore the mean resting heart rate （RHR）,β-blocker usage status and safety status of β-blocker in hospitalizations with coronary artery disease in 24 hospitals in Beijing,China. Methods This was an open,multi-center observational study. The trial enrolled 1570 hospitalized participants with coronary artery disease from Jun. 2012 to Sep 2012 in 24 hospitals in Beijing,China. The mean RHR,β-blocker usage status were recorded on the day of admission and discharge. Results The mean RHR on admission and discharge was 71 bpm ＋ 13.61 bpm vs 65.27 ± 9.96 bpm （P 〈 0.05 ）. The rate of reaching the standard of RHR when discharged was 35.92%. The rate of β-blocker usage was 80.06% vs 91.7%） （P = 0.1615）. The rate of usage of metoprolol tartrate was 60.38% vs 60.70% （P = 0.414）. The average dose of it was 29.55 ± 24.6 mg per day vs 16.38 ± 27.5 mg per day. Conclusion The success rate of RHR in 24 hospitals of Beijing is low. The rate of β-blocker usage and average dose of β-blocker are both low.