卡孕栓在宫颈发育不良患者人流术前的应用

Carboprost in cervical development application in patients with poor before artificial abortion

目的观察卡孕栓在初孕、宫颈发育不良者行人工流产术时软化、扩张宫颈、手术时间、术中出血量、人工流产综合反应及人工流产并发症，宫颈粘连等方面与未用药组的比较。方法选择年龄18-23岁初孕、宫颈发育不良、坚硬、孕6～8周要求行人工流产术的妇女64例，随机分为两组，观察组：无药物过敏史及前列腺素类药物禁忌症者，人工流产术前使用卡前列甲酯栓1mg；对照组：人工流产术前未使用任何药物。比较和计算两组手术时间、术中出血量、人工流产综合反应及人工流产并发症宫颈粘连的发生率。结果观察组手术时间，术中出血量明显低于对照组，人工流产综合反应及宫颈粘连等方面发生率低于未用药组；两组之间差异有统计学意义（P〈0．05）。结论人工流产术前使用卡孕栓显著降低了机械性扩张宫颈的难度，提高手术成功率，减少术中出血量，人工流产综合反应及人工流产并发症宫颈粘连等方面发生率显著降低，疗效确切，安全可靠。

Objective To observe the effect of carboprost in early pregnancy, cervical dysplasia underwent artificial abortion, dilatation of the cervix softening, operation time, amount of Needing during the operation, artificial abortion syndrome and complications of artificial abortion cervical adhesion and no treatment group comparison. Methods For selecting age 18-23 in early pregnancy, cervical dysplasia, hard, pregnant 6-8 week request induced abortionwomen in 64 cases, were randomly divided into 2 groups, the observation group： no history of drug allergy and prostaglandin drug contraindication before artificial abortion using carboprost methylate suppositorites lmg; control group： without the use of any drug before artificial abortion, calculation and comparison of 2 groups of operationoperation time, bleeding volume, artificial abortion syndrome and complications of artificial abortion in the incidence ofcervical adhesions. Results In the observation group, operation time, amount of bleeding in operation were significantly lower than those in the control group, the artificial abortion syndrome and cervical adhesion etc. the occurrence rate of lower than untreated group; there was statistically significant difference between the two groups（P〈0.05）. Conclusion Artificial abortion preoperative use of carboprost significantly reduced mechanical dilatation of the cervix of the difficulty, improve the success rate of operation, reduce the amount of bleeding during the operation,artificial abortion syndrome and complications of artificial abortion cervical adhesions and other aspects were significantly lower, curative effect is exact, safe and reliable.