凝血酶原时间和清蛋白检测在腹内高压中的意义

Clinical significance of prothrombin time and serum albumin in patients with intra-abdominal hypertension

目的探讨血浆凝血酶原时间(prothrombin time,PT)和血清蛋白(albumin,Alb)检测在腹内高压(IAH)患者中的临床意义。方法选取IAH患者30例,另取30例健康者作为对照组,分别检测检验指标PT和ALB。PT检测应用凝固酶法,Alb检测应用溴甲酚绿法。结果 IAH患者组PT、PTR高于对照组,差异有统计学意义(P<0.05),患者组PTA、Alb低于对照组,差异有统计学意义(P<0.05)。结论 IAH可引起凝血功能障碍及蛋白丢失,PT和Alb的检测有助于了解IAH患者的病情。

Objective To detect the significance of plasma prothrombin time （PT） and serum albumin （Alb） in pa- tients with intra-abdominal hypertension （IAH） . Methods Selected 30 patients with IAH, another 30 healthy persons as control group, were dectected PT and ALB. Coagulase method was used to dectect PT, bromocresol green method was used to dectect ALB. Results PT and PTR in IAH group were significantly higher than those in control group, the difference was statistically significant （ P 〈 0. 05 ） , PTA and ALB in IAH group were significantly lower than those in control group, the difference was statistically significant （ P 〈 0. 05 ） . Conclusion IAH may cause coagulation dysfunction and loss of protein, detection of PT and Alb is helpful to the understanding of the disease in patients with IAH.