980nm红激光治疗前列腺增生患者的疗效分析

The efficacy of 980nm laser therapy for benign prostate hyperplasia

目的：评价980nm红激光治疗前列腺增生患者的有效性和安全性。方法：总结我科2010年10月~2014年3月收治的前列腺增生患者的手术病例105例,其中980nm红激光手术组43例,经尿道等离子双极前列腺切除（PKRP）手术组62例,比较2组手术病例术前、术后第6个月的IPSS评分、QOL评分、最大尿流率（Qmax）、残余尿量（PVR）,分析2组病例的手术时间、术中出血量、膀胱冲洗时间、留置尿管时间、住院费用等相关指标。结果：2组患者术前IPSS评分、QOL评分、Qmax、PVR与术后第6个月指标相比,均存在显著性差异（P〈0.05）。组间比较发现,患者手术前后症状改善程度相近,差异无统计学意义（P〉0.05）。980nm红激光组手术和PKRP组手术时间、术中出血量、术后膀胱冲洗时间和术后留置尿管时间分别为59.6±18.6min比63.3±19.6min、210.7±45.3ml比410.5±66.9ml、26.2±11.5h比46.9±23.6h以及4.5±0.9d比6.1±1.4d（均P〈0.05）;平均手术费用分别为11000元和2000元（P〈0.05）。结论：980nm红激光治疗前列腺增生患者的短期手术效果与PKRP手术组相当;在术中出血量、术后膀胱冲洗时间、留置尿管时间等指标方面,980nm红激光手术组更有优势;但980nm红激光手术组手术费用较高。

Objective：To evaluate the efficacy and safety of 980 nm laser therapy for benign prostate hyperplasia.Methods：Data of 43 patients with BPH treated with 980 nm laser system were analyzed, and other 62 patients received transurethral plasma kinetic resection of prostate（PKRP）were taken as controls.International Prostate Symptom Score（IPSS）,quality of life（QOL）,preoperative maximal flow rate（Qmax）and post void residual urine volume（PVR）were compared both before and at 6 months after treatment.The mean operating time,blood loss during operation,bladder irrigating time and the mean postoperative indwelling catheter time were analyzed.Results：Comparing with the value at 6 months after operation,IPSS score,QOL score,Qmax and PVR had significantly been improved by either procedure（P〈0.05）.The degree of improvement in two groups was similar.The mean operation time,bleeding volume,irrigating time,catheterization time and operation cost in980 nm laser therapy group and PKRP group were 59.6±18.6 minutes vs. 63.3±19.6 minutes,210.7±45.3 ml vs.410.5±66.9 ml,26.2±11.5 hours vs. 46.9±23.6 hours,4.5±0.9 days 6.1±1.4 days and the cost was 11000 RMB vs 2000 RMB, respectively（P0.05 for all comparisons）.Conclusion：980nm laser therapy had similar efficacy as PKRP.It had fewer side effects but more expensive than PKRP.