摘要
Beagle犬是国际公认的实验用犬,常用于制备高血压实验动物模型。与诱发性高血压模型相比,自发性高血压模型更接近人类高血压疾病生理过程,如能获得遗传性自发高血压Beagle犬模型,将对人类高血压疾病研究具有重要意义。本文通过对300多只不同年龄段Beagle犬进行血压测定分析,结果表明血压总均值为161 mm Hg,并且随着Beagle犬年龄的增长而上升,为自发性高血压Beagle犬的研究提供一定的科研数据。
The beagle dog is the experimental dog admitted internationally, and it was commonly used in hypertension disease model. Compared to the induction model of hypertension, the spontaneously hypertension model is more similar to the physiological processes of human hypertension, and it will play a crucial role in the human hypertension research if we could generate the inherited spontaneously hypertension Beagle model. More than 300 Beagle dogs were used to analyze the blood pressure at different age .The results showed that the average SBP was 161 mmHg, and rised with age. Which provided the basic research data for the spontaneously hypertension Beagle model.
出处
《广东畜牧兽医科技》
2015年第1期44-46,共3页
Guangdong Journal of Animal and Veterinary Science
基金
国家科技支撑计划(2013BAK11B00)
广州市科研条件建设项目(穗科信字[2011]233-16)