参芪柔脉合剂治疗脑梗死患者颈动脉粥样斑块疗效分析

Clinical Study of Effect of Shenqi Roumai Decoction on Carotid Artery Atherosclerosis of Patients with Cerebral Infarction

目的:研究参芪柔脉合剂对脑梗死患者颈动脉粥样硬化斑块的治疗效果。方法:将150例脑梗死伴有颈动脉粥样硬化斑块形成的患者随机分为试验组和对照组,试验组给予参芪柔脉合剂结合辛伐他汀,对照组给予辛伐他汀,观察患者服药前后颈动脉斑块的内膜中层厚度(IMT)、斑块面积和血脂水平的变化。结果:6个月后,试验组患者颈动脉IMT、斑块面积、血脂水平均有显著变化,与对照组相比差异有统计学意义(P<0.05)。结论:参芪柔脉合剂对脑梗死患者颈动脉粥样硬化斑块有治疗作用。

Objective：To study the influence of Shenqi Roumai Decoction on the atherosclerosis plaque in carotid artery of cerebral infarction patients. Methods：A total of 150 patients with cerebral infarction and carotid artery atherosclerosis were randomly divided into study group and routine therapy control group. The study group was given Shenqi Roumai Decoction and Simvastatin Dispersible Tablets. The control group was treated with Simvastatin Dispersible Tablets for 6 months. We investigated the change and the significances of carotid intimal-medial thickness（IMT）,plaques area and blood lipid before and after treatment. Results：After 6 months administration of study group,there were significant changes in IMT,plaques area and blood lipid. Comparing with the control group,the differences were significant statistically. Conclusion：The treatment of Shenqi Roumai Decoction can stabilize the plaque of carotid artery of patients with cerebral infarction.