NT-proBNP可预测急性前壁心肌梗死对比剂肾病的发生被引量：1

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摘要目的探讨血浆N-末端脑利钠肽前体(NT-pro BNP)是否可预测急性前壁心肌梗死(AMI)患者直接经皮冠脉介入(PCI)术后对比剂肾病(CIN)的发生。方法随机入选行直接PCI术的AMI患者102例,患者术中应用低渗非离子造影剂碘普罗胺(商品名:优维显),术前检测血清肌酐、NT-pro BNP,术后24、48、72 h复查血清肌酐。结果两组共入选患者102例,共发生CIN为15例,发生率为14.7%。平均年龄(60±11)岁,男性74例、女性28例,其中吸烟65例(64%)。发生CIN与未发生CIN的两组患者危险因素对比发现:年龄,入院时KILLIP(Ⅱ-Ⅳ),慢性心衰病史等方面具有显著差异,P值分别为<0.01,0.03,0.04。术前血清NT-pro BNP水平与CIN发生的相关性分析显示血清NT-pro BNP水平与CIN的发生呈正相关,发生CIN的风险随NT-Pro BNP水平增加而增加(P=0.022)。结论术前血清NT-pro BNP水平与CIN的发生成正相关,是预测急性前壁心肌梗死患者行急诊PCI术后发生对比剂肾病的标志物。

作者崔丽杰李占全苗志林方芳

机构地区辽宁省沈阳市人民医院心内科

出处《中外医疗》 2014年第31期114-115,118,共3页 China & Foreign Medical Treatment

关键词 NT-pro BNP AMI 对比剂肾病

分类号 R542.22 [医药卫生—心血管疾病]

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参考文献8

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