鼻塞式CPAP治疗早期新生儿肺透明膜病探讨

Observation on the Effect of Nasal CPAP on Early Neonatal Hyaline Membrane Disease

目的就鼻塞式CPAP治疗早期新生儿肺透明膜病进行探讨。方法选择该院2012年1月—2013年12月所收治的100例新生儿肺透明膜病患者为研究对象,随机分成两组,每组50例,分别是对照组和实验组。对照组采用常规治疗方式,而实验组在对照组基础上采用鼻塞式CPAP治疗。结果实验组有效46例(92%),无效4例(8%),有效率为92%;而对照组有效37例(74%),无效13例(26%),有效率为74%;两组患者的有效率具有较为明显的差异,差异有统计学意义(P<0.01)。结论鼻塞式CPAP治疗早期新生儿肺透明膜病疗效较佳,能够大幅度提高患儿存活率,改善NHMD症状,治愈率高,值得推广应用。

Objective To observe the effect of nasal CPAP in the treatment of early neonatal hyaline membrane disease. Methods 100 newborns with hyaline membrane disease admitted in our hospital from January 2012 to December 2013 were selected as the subjects and randomly divided into two groups, the control group and the experimental group, with 50 cases in each. The control group was treated by the conventional treatment, and the experimental group was treated by nasal CPAP based on the treatment given to the control group. Results In the experimental group, the treatment was effective in 46 cases （92%）, ineffective in 4 cases （8%）, the effective rate was 92%; in the control group, the treatment was effective in 37 cases（74%）, ineffective in 13 cases（26%）, the effective rate was 74%; the difference between the groups was statistically significant （P〈0.01）. Conclusion Nasal CPAP has good effect on early neonatal hyaline membrane disease, which can significantly improve the survival rate of the children and the NHMD symptoms with high cure rate, so it is worthy of popularization and application.