病毒性角膜炎患者微量元素及机体综合免疫状态的变化

Change of trace elements and body comprehensive immune state of patients with viral keratitis

目的:研究及探讨病毒性角膜炎患者微量元素及机体综合免疫状态的变化情况。方法:选取2011-12/2014-02于本院进行诊治的62例病毒性角膜炎患者为观察组,同期的62名健康体检者为对照组,将两组人员的血清及泪液Zn及Cu、细胞免疫及红细胞免疫指标进行比较,同时比较观察组中不同分类与严重程度患者的检测结果。结果:观察组的血清及泪液Zn低于对照组,血清及泪液Cu则高于对照组,细胞免疫及红细胞免疫指标均差于对照组,且观察组中轻中重度患者之间也存在明显差异(P<0.05),而单纯疱疹和带状疱疹患者之间则无明显差异(P>0.05)。结论:病毒性角膜炎患者微量元素及机体综合免疫状态的变化较为明显,且其检测水平受角膜炎的严重程度影响较大。

AlM：To study and investigate the change situation of trace elements and body comprehensive immune state of patients with viral keratitis.METHODS：Sixty-two patients with viral keratitis in our hospital from December 2011 to February 2014 were selected as observation group, 62 healthy persons with health education at the same time were the control group, then the serum and tear Zn, Cu, cellular immunity and erythrocyte immunity of two groups were compared, and the detection results of observation group with different types and severity degree were compared.RESULTS：The serum and tear Zn of observation group was all lower than that in control group, serum and tear Cu was higher than that in control group, cellular immunity and erythrocyte immunity indexes were all worse than that in control group, the detection results of observation group with mild, moderate and severe infection had significant differences （P〈0. 05）, while the detection results of observation group with herpes simplex keratitis and herpes zoster keratitis had no significant differences （P〉0. 05）.CONCLUSlON： The change of trace elements and body comprehensive immune state of patients with viral keratitis are obvious, and the severity degree for the detection levels of keratitis are greater.