2型糖尿病住院患者糖尿病视网膜病变的相关危险因素分析

Prevalence and risk factors of diabetic retinopathy in type 2 diabetic inpatients

目的:探讨2型糖尿病视网膜病变(DR)的发病危险因素。方法:选择2014-01/06收治的2型糖尿病患者380例,分为DR组126例和对照组即糖尿病无视网膜病变(NDR)组254例,进行询问病史、体格检查、实验室检查和相关辅助检查,采用Logistic回归分析法对DR的相关危险因素进行单因素及多因素分析。结果:单因素Logistic回归分析结果表明,病程、收缩压、甘油三酯、总胆固醇、低密度脂蛋白、尿蛋白、眼压、颈动脉内中膜厚度、周围神经病变是DR发生的相关危险因素。对以上因素进行多因素Logistic回归分析,只发现病程是DR发生的相关危险因素。结论:DR的发生是多因素共同作用的结果,病程是DR发生的独立危险因素。

AlM： To investigate the risk factors of diabetic retinopathy （ DR） in type 2 diabetes patients.METHODS：A total of 380 cases of type 2 diabetes were selected from January 2014 to June 2014, divided into DR group （126 cases） and non-diabetic retinopathy （ NDR） as control group （254 cases）, all patients were underwent medical history, physical examinations, laboratory and assistance examinations. The prevalence and single factor and multiple factors of DR were analysed by the logistic regression model.RESULTS： The univariate logistic regression analysis showed that DR was associated with diabetes duration, systolic blood pressure, triglyceride, total cholesterol, low - density lipoprotein, urine protein, intraocular pressure, carotid intima - media thickness, peripheral neuropathy disease was the related risk factors for DR. ln multiple logistic regression analysis, only duration was the related risk factors for DR.CONCLUSlON：The occurrence of DR is the outcome of combined action of multiple factors, duration is an independent risk factor for occurrence of DR.