二维斑点追踪成像评价左前降支病变心肌梗死病人左心室长轴收缩功能

EVALUATION OF LEFT VENTRICULAR LONG-AXIS SYSTOLIC FUNCTION USING TWO-DIMENSIONAL SPECKLE TRACKING IMAGING IN PATIENTS WITH MYOCARDIAL INFARCTION DUE TO LESION OF LEFT ANTERIOR DESCENDING ARTERY

目的应用二维斑点追踪成像（STI）评价冠状动脉左前降支完全和不完全闭塞所致心肌梗死病人的左心室局部长轴收缩功能。方法选择冠状动脉造影示左前降支动脉近端完全闭塞的心肌梗死病人（T-LAD组）30例、不完全闭塞的心肌梗死病人（S-LAD组）25例和健康志愿者（正常对照组）30例。应用二维STI测量室间隔、左心室前壁、侧壁、下壁的基底段、中间段、心尖段的长轴收缩期峰值应变率（SRs）。结果心肌梗死病人室间隔及左心室前壁、侧壁的中间段、心尖段SRs均小于正常对照组（F=7.49~83.43,P〈0.05、0.01）,T-LAD组室间隔及左心室前壁、侧壁心尖段SRs较S-LAD组减低（F=16.00~83.43,P〈0.01）。结论 STI能够准确评价左前降支完全和不完全闭塞所致心肌梗死病人左心室局部长轴收缩功能变化。

Objective To evaluate the left ventricular long-axis systolic function in patients with myocardial infarction （MI） caused by total or subtotal occlusion of left anterior descending artery （LADA） using two-dimensional speckle tracking ima- ging （2DSTI）. Methods According to coronary angiography, 30 MI patients caused by total occlusion of LADA, and 25 MI pa- tients due to subtotal occlusion of LADA were enrolled in this study. A normal control group consisted of 30 healthy volunteers. The longitudinal peak systolic strain rates （LPSSRs） were measured at basal, middle and apical segment in different left ventricular walls （septal, lateral, inferior and anterior） using 2DSTI. Results The values of LPSSRs of middle and apical segments in sep- tal, lateral, inferior and anterior were significantly lower in the patients than the normal controls （F = 7.49- 83.43,P 〈 0.05, 0.01）. Compared with subtotal occlusion group, the values of LPSSRs of apical segment in septal, lateral, inferior and anterior in the total occlusion group were lower （F=16.00-83.43,P〈0.01）. Conclusion Two-dimensional speckle tracking imaging can accurately assess left ventrieular long-axis systolic function in patients with myocardial infarction caused by total or subtotal occlu- sion of left anterior descending artery.