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子痫前期孕妇血管生成素2表达研究进展 被引量：1

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摘要 血管生成素家族(Angs)是一组具有内皮细胞特异性的促血管生成因子,是惟一含受体激动剂和抑制剂的促血管生成因子。Angs通过与其受体(Tie)结合参与血管的生成及退化,有维护血管稳定的作用。血管生成素2(Ang-2)可使血管通透性增加,稳定性下降,促进新生血管的生成。Ang-2参与胎盘血管的形成,影响胚胎发育。在孕妇的血清、胎盘及胎儿脐带血中均可检测到Ang-2的表达,子痫前期孕妇Angs/Tie系统基因表达失控,Ang-2可能参与子痫前期的发病。
作者 王丽静 董瑞峰 张倩 胡海燕 徐风森
机构地区 青岛市市立医院产科
出处 《青岛大学医学院学报》 CAS 2015年第1期119-120,123,共3页 Acta Academiae Medicinae Qingdao Universitatis
关键词 血管生成素2 先兆子痫 胎盘 血浆 脐血 综述
分类号 R714.244 [医药卫生—妇产科学]
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参考文献22

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二级参考文献15

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青岛大学医学院学报
2015年 第1期

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