胃肠安丸联合活菌制剂治疗感染后肠易激综合征的临床疗效观察

Clinical observation of Weichangan pills combined with living intestinal bacteria preparation on post-infection irritable bowel syndrome

[目的]探讨胃肠安联合肠道活菌制剂治疗感染后肠易激综合征腹泻型的临床疗效。[方法]将76例感染后肠易激综合征腹泻型患者,随机分为2组,每组各38例。治疗组口服胃肠安丸0.1g,3次/d;复方嗜酸乳杆菌片1g,3次/d;马来酸曲美布汀片0.2g,3次/d。对照组口服马来酸曲美布汀片0.2g,3次/d。在连续治疗第2周和第4周对患者大便次数和临床症状进行疗效评估,并观察不良反应。[结果]治疗第2周和第4周2组的临床疗效比较,差异均有统计学意义(P<0.05)。[结论]胃肠安丸联合肠道活菌制剂治疗感染后肠易激综合征腹泻型疗效显著,值得临床推广。

[Objective]To explore the clinical effects of the therapeutic regimen Weichangan pills com- bined with living intestinal bacteria preparation on post infection irritable bowel syndrome（PI-IBS）. [Meth- ods]Seventy-six patients of PI-IBS were randomly assigned into two groups. The treatment group was ad- ministered as follows- Weichangan pills 0.1 g, po, tid. Eosinophil-Lactobacillus Compound tablets, 1 g, po, tid,and Trimebutine Maleate tablets 0.2 g, po, tid, While the control group was only administered Trime- butine Mateate tablets 0.2 g, po, tid. The clinical evaluations including fecal frequency, clinical symptoms and side effects were undertaken after 2 and 4 weeks＇ treatments. [Results]Significant differences were ob- served in clinical evaluations after 2 and 4 weeks＇ treatments（P〈0.05）. [Conclusion]The therapeutic regi- ment Weichangan pills combined with living intestinal bacteria preparation on post-infection irritable bowel syndrome（PI-IBS）is effective in clinical evaluation, which is worthwhile for clinical application.