活血通窍汤治疗利培酮所致高催乳素血症导致闭经的临床研究

Huoxue Tongqiao Decoction in the Treatment of Risperidone Induced Hyperprolactinemia Caused Clinical Study of Amenorrhea

目的探讨活血通窍汤治疗利培酮所致的高催乳素血症而导致闭经的临床疗效。方法回归性分析2013年6月~2014年5月十堰市中医医院精神病科56例精神分裂症女性患者因服用利培酮所致高催乳素血症而导致闭经的临床资料,分析所有患者服用活血通窍汤前后催乳素指标及闭经疗效。结果与治疗前相比,患者在治疗后的催乳素水平显著下降（P〈0.05）,闭经的总有效率为96.43%。结论活血通窍汤可有效治疗利培酮所致高催乳素血症而导致的闭经。

Objective To investigate hyperprolactinemia Huoxue Tongqiao Decoction in the treatment of risperidone induced amenorrhea caused clinical curative effect. Methods regression analysis clinical data from 2013 June to 2014 May in Shiyan City Hospital of Traditional Chinese Medicine of psychiatry in 56 cases of female patients with schizophrenia by risperidone induced hyperprolactinemia and cause amenorrhea, analysis of all patients before and after taking Huoxue Tongqiao Decoction curative effect of prolactin index and amenorrhea. Results compared with the before condition, the level of prolactin in the patients decreased significantly after the treatment （ P〈0.05 ） , amenorrhea＇ s, total efficiency was 96.43 %. Conclusion Huoxue Tongqiao decoction may be effective in the treatment of risperidone induced hyperprolactinemia and lead to amenorrhea.