挹神汤加减治疗女性围绝经期失眠症36例的临床研究

Clinical Study of Yishen Decoction in the Treatment of Perimenopausal Insomnia in 36 Cases

目的：观察挹神汤治疗女性围绝经期失眠的疗效。方法：收集2013年9月~2014年5月我院围绝经期失眠患者72例,分为观察组和对照组各36例,对照组用艾司唑仑片治疗,观察组用挹神汤加减治疗,疗程30天。比较两组睡眠改善情况、临床疗效、中医症候疗效。结果：（1）观察组及对照组治疗后阿森斯量表评分（7.3±1.2、9.6±1.7）与治疗前比较均有不同程度降低,差异有统计学意义（P〈0.05）,观察组评分降低程度大于对照组,两组差异有统计学意义（P〈0.05）。（2）观察组失眠总有效率为94.44%,对照组为77.78%,两组差异有统计学意义（P〈0.05）。（3）观察组中医症候疗效总有效率为91.67%,对照组为72.22%,两组差异有统计学意义（P〈0.05）。结论：挹神汤加减治疗围绝经期失眠患者疗效显著,可显著改善患者的失眠症状体征,提高临床治疗有效率,安全性高。

Objective： To observe the curative effect of Yishen Decoction in treating insomnia perimenopausal women.Methods： Between September 2013-May 2014,We Collected 72 patients suffering from this disease who were randomized into two groups,36 women receive Yishen Decoction,the others use Estazolam.30 days of treatment.Then compare the situation of sleep,clinical and syndrome curative effect of two groups.Results：（l）Because the treatment ,the two grougs have the different degrees to reduce Athens rating scale,specially the observation group,and the difference is statistically significant（P〈0.05）.（2）The total effective to insomnia of the observation group is 94.44%,the control group is 77.78%.（3）Thc total effective to TCM syndrome of the observation group is 91.67%,the other is 72.22%. Conclusion： Yishen Decoction carl significantly improve sleep of perimenopanse insomnia,also have high safety and low side effects.