中心静脉压水平与脑外伤患者的早期疗效分析

The analysis of the effects of the central venous pressure level on early efficacy of treatment with traumatic brain injury

目的：探讨中心静脉压（CVP）水平对脑外伤患者的早期疗效的影响。方法：根据格拉斯（GCS）评分将脑外伤患者分为3组：轻度组、中度组、重度组。分别将3组随机分为较低CVP值组（5~8cmH2O）、较高CVP值组（9~12cmH2O）,根据瞳孔、神志、GCS评分及颅脑CT的改善,分3个时间（24h、72h和1周）观察其变化。结果：较低CVP值组的早期疗效优于较高CVP值组。结论：在患者CVP水平保持在5~8cmH2O时,既可保证患者脑灌注压,又不至于加重脑水肿,早期疗效较好。

Objective：To discuss the effects of central venous pressure （CVP） level on early efficacy of treat- ment with traumatic brain injury （TBI）. Method：According to Glasgow coma scale （GCS）, traumatic brain injury patients were divided into three groups：mild, moderate and severe group. The three groups were randomly divided into a lower CVP group （5~8 cmH20） and the higher CVP group （9~12 cmH20）. According to the pupil con- sciousness,GCS and brain CT,to observe the changes on the three time points （24 hours, 72 hours and 1 week）. Result： The lower CVP group is superior to the higher CVP group of matter the in early efficacy. Conclusion： The early efficacy of treatment is better when the CVP levels stayed around the 5 ~ 8 cmH2 O, which can ensure the cer- ebral perfusion pressure without aggravating cerebral edema.