摘要
A simple, water-soluble, Fe3+-selective fluorescent probe, derived from rhodamine B, was synthesized and characterized. The probe exhibits a fluorescence response toward Fe3+ with acceptable sensitivity and selectivity and even facilitates visual or naked-eye detection of Fe3+. The experiment results show that the response of the probe to Fe3+ is pH-independent over a wide range of 4.0-10.0. In addition, fluorescence microscopic imaging experiments have proven that the probe is cell permeable and can be used for monitoring intracellular Fe3+ in living cells.
A simple, water-soluble, Fe3+-selective fluorescent probe, derived from rhodamine B, was synthesized and characterized. The probe exhibits a fluorescence response toward Fe3+ with acceptable sensitivity and selectivity and even facilitates visual or naked-eye detection of Fe3+. The experiment results show that the response of the probe to Fe3+ is pH-independent over a wide range of 4.0-10.0. In addition, fluorescence microscopic imaging experiments have proven that the probe is cell permeable and can be used for monitoring intracellular Fe3+ in living cells.
基金
supported by Natural Science Foundation of Fujian Province(No.2013H0019)
the Science Foundation of Education Department of Fujian Province(No.JA11064)
the Open Foundation of the State Key Laboratory of Fine Chemicals(No.KF1307)
the Open Foundation of Ministry of Education Key Laboratory of Synthetic and Natural Functional Molecular Chemistry