不同营养方式在恶性梗阻性黄疸患者经皮肝穿刺胆管引流术后免疫功能恢复程度中的效果比较

The immune function recovery comparison of different nutrition ways in ma-lignant obstructive jaundice after percutaneous transhepatic cholangial drainage

目的对比分析肠内营养和肠外营养下恶性梗阻性黄疸患者行经皮肝穿刺胆管引流术（PTCD）后的免疫恢复情况。方法选取2012年4月~2014年10月来本院诊断为恶性梗阻性黄疸患,且进一步行PTCD手术的患者60例,随机分为肠内营养组和肠外营养组各30例,分别于手术前,手术后5、10 d对比分析两组患者免疫功能的差异。结果 60例患者均成功完成肠内营养及肠外营养,无明显不良反应;PTCD术后,两组患者的免疫力均呈不同程度恢复,肠内营养组治疗后5、10 d,免疫指标（CD^4＋、CD^8＋、CD^4＋/CD^8＋、IgA、IgG、IgM）恢复程度明显高于肠外营养组,差异有统计学意义（P〈0.05）。结论恶性梗阻性黄疸患者PTCD术后,肠内营养更有利于患者免疫功能恢复。

Objective To compare the differences of immune function recovery with different nutrition ways in malignant obstructive jaundice after percutaneous transhepatic cholangial drainage（PTCD）. Methods 60 patients diagnosed as malignant obstructive jaundice in our hospital from April 2012 to October 2014 and who were taken with PTCD were selected,and were divided into enteral nutrition group and parenteral nutrition group.The immune function was compared between the two groups. Results All these patients successfully completed enteral nutrition and parenteral nutrition,and had no bad reaction.The CD^4＋,CD^8＋,CD^4＋/CD^8＋,IgA,IgG,IgM increased in both groups,and immune function of enteral nutrition group recovered better than that of parenteral nutrition（P〈0.05）. Conclusion Enteral nutrition can help to recovery immune function of patients who are diagnosed with malignant obstructive jaundice after PTCD.