持续性房颤与血浆硫化氢水平的关系研究

Correlation research on persistent atrial fibrillation and the level of plasma hydrogen sulfide

目的观察持续性房颤患者血浆硫化氢（H2S）水平的变化,研究其与持续性房颤的关系。方法选择本院2013年4月~2014年7月心内科住院的持续性房颤患者60例为病例组,其中男性32例,女性28例,平均年龄（61.07±10.35）岁。选取同期健康人60例为对照组,其中男性30例,女性30例,平均年龄（60.13±9.64）岁。采用敏感硫电极法测定血清H2S水平。结果病例组血浆H2S水平显著低于对照组（P〈0.01）。结论持续性房颤的发生可能与血浆H2S水平的降低有关。

Objective To observe the change on level of plasma hydrogen sulfide（H2S） in patients with persistent atrial fibrillation,and research on their correlation. Methods 60 patients with persistent atrial fibrillation admitted into cardiology department in our hospital from April 2013 to July 2014 were selected as medical case group,among them,male was 32 cases and female was 28 cases,the average age was（61.07±10.35）years old.60 healthy persons were selected as control group with male and female half and half,the average age was（60.13±9.64）years old.The level of plasma H2 S was tested by sensitive sulphur electrode. Results The level of plasma H2 S in medical case group was greatly lower than that in control group（P〈0.01）. Conclusion Onset of persistent atrial fibrillation may be related to the level of plasma H2 S decreasing.