消旋卡多曲辅助治疗小儿轮状病毒性肠炎的效果观察

Effect observation of racecadotril auxiliarily treating Rotavirus enteritis in children

目的探讨消旋卡多曲辅助治疗小儿轮状病毒性肠炎的效果。方法选取我院收治的80例轮状病毒性肠炎患儿,按照随机数字表法均分为对照组和观察组,对照组给予蒙脱石散口服,观察组给予消旋卡多曲联合蒙脱石散治疗,比较两组的总有效率、临床症状恢复时间和不良反应发生情况。结果观察组的总有效率为95.0%,显著高于对照组的80.0%(P<0.05);观察组的止吐时间、脱水纠正时间、大便次数及性状正常时间均短于对照组(P<0.05);两组患儿均无严重不良反应发生。结论消旋卡多曲辅助治疗小儿轮状病毒性肠炎的效果确切,安全性高,可有效缓解临床症状,值得临床广泛推广应用。

Objective To investigate the effect of of racecadotril auxiliarily treating Rotavirus enteritis in children.Methods 80 children with Rotavirus enteritis treated in our hospital were randomly and evenly divided into the control group and observation group according to the random number table method.The control group was given oral montmorillonite powder.The observation group was treated with racecadotril combined with montmorillonite powder.The total effective rate,clinical symptoms recovery time and adverse reaction occurrence of the two groups were compared. Results The total effective rate of observation group（95.0%） was significantly higher than that of the control group（80.0%）（P〈0.05）.The antiemetic time,dehydration corrected time,stool frequency and traits normal time of the observation group were significantly shorter than that of the control group respectively（P〈0.05）.Both of two groups had no serious adverse events. Conclusion Racecadotril auxiliarily treating Rotavirus enteritis in children has exact effect with higher safety.It can effectively relieve clinical symptoms.It is worthy of clinical widely promotion and application.