期刊文献+

HBsAg阳性孕妇乙型肝炎防治知识调查及乙型肝炎疫苗联合HBIG阻断乙型肝炎病毒母婴传播的效果 被引量:8

Investigation of hepatitis B prevention knowledge of HBs Ag positive pregnant women and effect of the hepatitis B vaccine combined with HBIG in the blocking of mother-to-fetus transmission of hepatitis B virus
下载PDF
导出
摘要 目的探讨乙型肝炎疫苗联合乙型肝炎免疫球蛋白(HBIG)阻断乙型肝炎病毒(HBV)母婴传播的效果。方法选择2009年1月~2011年6月本院妇产科收治的116例乙型肝炎表面抗原(HBs Ag)阳性的乙型肝炎产妇以及已按照免疫程序注射过HBIG以及乙型肝炎疫苗的年龄为1岁的婴儿作为研究对象,采用自制调查问卷对产妇进行乙型肝炎防治知识调查,检测婴儿血清HBs Ag。结果 HBs Ag阳性产妇对于乙型肝炎能够通过母婴传播的知晓率较高,认为乙型肝炎疫苗和HBIG可以预防乙型肝炎母婴传播者所占比例为74.14%。受检婴幼儿中,HBs Ag检测阳性11例(9.48%),阻断成功率为90.52%。母亲为乙肝大、小三阳所生的婴儿HBs Ag阳性率分别为14.71%和2.08%,两者比较差异有统计学意义(P〈0.05);母亲孕期接种和未接种HBIG的婴儿HBs Ag阳性率分别为6.58%和15.00%,剖腹产以及顺产的婴儿HBs Ag阳性率分别为13.51%和7.59%,人工喂养和母乳喂养的婴儿HBs Ag阳性率分别为9.09%和8.54%,以上观察指标比较差异均无统计学意义(P〉0.05)。结论加强HBV感染孕妇的乙型肝炎防治知识健康宣教,并按照免疫程序对新生儿联合接种乙型肝炎疫苗和HBIG,可以有效降低乙型肝炎的母婴传播率。 Objective To observe the effect of hepatitis B vaccine combined with hepatitis B immunoglobulin(HBIG) to block mother-to-fetus of hepatitis B virus(HBV). Methods 116 pregnant women of positive hepatitis B surface antigen(HBs Ag) and infant injected HBIG and hepatitis B vaccine at the age of 1 years according to the immunization program from January 2009 to June 2011 in our hospital were selected as the research object.The questionnaire investigation of hepatitis B prevention knowledge on maternal was used and infant serum HBs Ag was detected. Results The rate of mother-to-fetus of hepatitis B virus in pregnant women of HBs Ag positive was higher.There was 74.14% of the people thought that the hepatitis B vaccine and HBIG could prevent mother to child transmission of hepatitis B.The infants tested HBs Ag positive in 11 cases,the positive rate of HBs Ag was 9.48%,blocking the success rate was 90.52%.The positive rate of babies with mother were 14.71% and 2.08%,there was significant difference between the two groups(P〈0.05).The positive rate of maternal infant HBs Ag inoculated and non inoculated HBIG was 6.58% and 15%.The positive rate of babies with cesarean section and vaginal delivery was 13.51% and 7.59%.The positive rate of HBs Ag of artificial feeding and breast-feeding infants was 9.09% and 8.54%,the above observation indexes of two groups was not significant(P〉0.05). Conclusion To strengthen prevention and control of hepatitis B knowledge health education of pregnant women infected with HBV,and in accordance with the immunization program on neonatal joint vaccination of hepatitis B vaccine and HBIG,can effectively reduce the rate of mother-to-fetus transmission of hepatitis B.
作者 杨少鹏 李静
出处 《中国当代医药》 2015年第3期183-185,共3页 China Modern Medicine
关键词 乙型肝炎防治知识 乙型肝炎疫苗 乙型肝炎免疫球蛋白 乙型肝炎 母婴传播 Knowledge of hepatitis B prevention Hepatitis B vaccine Hepatitis B immunoglobulin Hepatitis B Mother-to-fetus transmission
  • 相关文献

参考文献14

二级参考文献81

共引文献131

同被引文献66

  • 1胡春秀,罗亚莉.孕妇感染乙肝病毒对母婴的影响[J].兰州医学院学报,2004,30(2):31-33. 被引量:9
  • 2孟钊,肖小敏,何明娇,徐玉苑,李耘.乙肝免疫球蛋白阻断乙肝病毒母婴垂直传播的研究[J].中国优生与遗传杂志,2005,13(9):49-51. 被引量:18
  • 3佘毅敏,黄锦红,周晓真,王丽梅.抗-HCV检测设置灰区的探讨[J].中国输血杂志,2006,19(2):136-137. 被引量:11
  • 4孙莲英,曾昭长,陈海云,符振旺,陈少明,闫秀娟,邓海英,潘正帆.海南省人群乙型肝炎血清流行病学调查研究[J].中国热带医学,2007,7(2):182-184. 被引量:27
  • 5范祎,肖小敏.分娩方式对乙肝病毒母婴垂直传播影响的Meta分析[J].中国妇幼保健,2007,22(27):3787-3789. 被引量:16
  • 6R.Palmer Beasley,George CHIN-YUN LEE,Cheng-Hsiung Roan,Lu-Yu Hwang,Chung-Chi Lan,Fu-Yuan Huang,Chiung-Lin Chen.PREVENTION OF PERINATALLY TRANSMITTED HEPATITIS B VIRUS INFECTIONS WITH HEPATITIS B IMMUNE GLOBULIN AND HEPATITIS B VACCINE. The Lancet . 1983
  • 7Gopal Rao G,Jeanes A,Russell H.Effectiveness of shortterm,enhanced,infection control support in improving compliance with infection control guidelines and practice in nursing homes a cluster randomized trial[J].Epidemiology and Infection,2009,137(137):1465-1471.
  • 8Addo-Yobo E,Anh D D,El-Sayed H F,et al.Outpatient treatment of children with severe pneumonia with oral amoxicillin in four countries:The MASS study[J].Tropical Medicine International Health,2011,16(8):995-1006.
  • 9van der Sande M A,Waight P,Mendy M,et al.Longterm protection against carriage of hepatitis B virus after infant vaccination[J].J Infect Dis,2006,193(11):1528-1535.
  • 10Kripke C.Hepatitis B vaccine for infant of HBs Ag-positive mothers[J].Am Fam Physician,2007,75(1):49-50.

引证文献8

二级引证文献36

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部