摘要
目的探讨艾滋病患者感染不同病原体后胸部CT特征、CD4＋T细胞计数相关性。方法回顾性分析我院收治的70例感染不同病原体的艾滋病患者胸部CT影像特征、CD4＋T细胞计数检测结果。结果70例患者胸部CT显示病变范围：单肺分布（11例，15．7％）、双肺分布（34例，48．6％）、弥漫分布（20例，28．6％）。影像特征前5位：胸内淋巴结肿大（45例，64．3％）、斑片状影（39例，55．7％）、磨玻璃影（21例，30．0％）、胸膜肥厚或胸腔积液（15例，21．4％）、结节影（10例，14．3％）。分组后CD4＋T细胞计数≤50个／μl组的弥漫分布、结节影比率则显著高于50个／“1〈CD4＋T细胞计数〈100个／μl及≥100个／ul两组，按感染不同病原体分组后发现单肺分布、弥漫分布、斑片状影、树芽征、胸内淋巴结肿大、结节影、空洞具有显著差异。结论艾滋病患者胸部CT特征及CD4＋T细胞计数提示病原体种类，因此了解艾滋病胸部CT的特征、CD4＋T细胞计数，有利于对病原体感染的早期诊断、治疗。
Objective To investigate the correlation of chest CT features and CD4＋T lymphocyte count after patients with acquired immune deficiency syndrome （AIDS） were infected by different pathogens. Methods A retrospective analysis on the chest CT image features and CD4＋T lymphocyte count in 70 cases of AIDS who were infected by different pathogens in our hospital was conducted. Results The chest CT in 70 cases of AIDS showed single lung distribution （11 cases, 15.7%）, double lung distribution （34 cases, 48.6%）, and diffuse distribution （20 cases, 28.6%）, The top five image features were intrathoracic lymphadenectasis （45 cases, 64.3%）, patchy shadows （39 cases, 55.7%）, ground glass opacity （21 cases, 30.0%）, pleural thickening or pleural effusion （15 cases, 21.4%）, and nodule （10 cases,14.3%）. The incidence of diffuse distribution and nodules in CD4＋T lymphocyte count 50/μl group was significantly higher than that in 50/μl 〈CD4＋T lymphocyte count 〈100/μl group and ≥100/μl group. There were significant differences in single lung distribution, diffuse distribution, patchy shadows,tree-in-bud,intrathoracic lymphadenectasis,nodules,and cavity among different pathogen groups. Conclusions The chest CT features and CD4＋T lymphocyte count in AIDS patients suggest pathogenic species. Therefore, it is helpful for the early diagnosis and treatment of pathogens infection to understand the chest CT characteristic and CD4＋ T lymphocyte count in AIDS patients.
出处
《国际呼吸杂志》
2015年第4期253-256,共4页
International Journal of Respiration
