卵巢交界性肿瘤与生殖的关系

Relationship of borderline ovarian tumors and reproduction

卵巢交界性肿瘤（BOTs）为低度恶性潜能的肿瘤，生长缓慢，无间质浸润性。多发于育龄期妇女，预后良好，10年生存率约为95％。发病率占所有卵巢肿瘤的8％～10％。年轻患者可以行保留生育力的保守性手术治疗。保守性手术后自然受孕率近50％。因此，尽管进行了保守手术，其中一些患者会经历不育。对于持续不孕的患者，部分患者可以采用辅助生育（ART）的方法来治疗。但ART对BOTs的自然病程的作用尚有争议。

Borderline ovarian tumours （BOTs） known as tumours of low malignant potential, have an indolent disposition, do not destructively invade the underlying ovarian stroma. They are more likely to be diagnosed in women of reproductive age and have a favourable prognosis, with more than 95% of women surviving ten years beyond diagnosis. They represent around 8%-10% of all ovarian neoplasms. Conservative treatment can be an option in young patients who wish to preserve their fertility. After conservative treatment the spontaneous pregnancy rate is nearly 50%. In spite of conservative management for BOTs, some of these patients will experience infertility. In case of persistent infertility, it seems that the use of assisted reproductive technology （ART） could be proposed in selected cases. The role of ART in the natural history of borderline tumour of the ovary is still debated in the literature.