缬沙坦、硝苯地平控释片联合吲哒帕胺阶段性治疗高血压亚急症疗效观察

Clinical observation on treating hypertensive urgency based on stages with valsartan, GITS plus indapamide

目的:观察缬沙坦、硝苯地平控释片联合吲哒帕胺治疗高血压亚急症的临床疗效,探讨原发性高血压亚急症的口服药物治疗方案。方法:选择原发性高血压亚急症患者247人,给予缬沙坦、硝苯地平控释片、吲哒帕胺治疗8周后,严密观察患者收缩压、舒张压、心率、生化指标等项目。结果:治疗前后收缩压、舒张压均有显著统计学差异(P<0.01)。结论:口服药物治疗原发性高血压亚急症选择缬沙坦-硝苯地平控释片-吲哒帕胺方案,疗效可靠,可以代替静脉用药,避免了对血压较高而无器官损害患者的过度治疗。

Objective： To observe clinical effects ofvalsartan, nifedipine controlled release tablets plus indapamide on hypertensive urgencies, and to study oral drugs therapeutic schedule of primary hypertensive urgencies. Methods： 247 patients with primary hypertensive urgencies were selected and given 8 weeks＇ treatment with valsartan, nifedipine controlled release tablets plus indapamide. Systolic pressures, diastolic pressure, heart rate, biochemical criterion in patients were observed. Results： Before and after the treatment, systolic blood pressure and diastolic blood pressure were significantly statistical difference （P〈0.01）. Conclusion： Valsartan, GITS plus indapamide were confirmed with good efficacy on hypertensive urgency, and could take the place of vein pharmacy, and avoid overtreatment for patients whose blood pressure is higher but have no organ damage.