小儿肺炎克雷伯菌检出率及耐药性分析

The detection rate and drug resistance analysis of pediatric pneumonia klebsiella bacteria

目的分析小儿肺炎克雷伯菌检出率及其耐药性情况,以便为临床诊治提供依据。方法选取2012年1月-2013年12月医院收治的小儿肺炎患儿530例作为研究对象,回顾性分析其临床资料,皆进行痰标本细菌学检测,检出克雷伯菌株后进行药敏试验,总结分析克雷伯菌检出率及其耐药性情况。结果 530例小儿肺炎痰标本中检出病原菌232例,其中检出克雷伯菌70株(30.17%),检出率为13.21%(70/530);药敏试验结果显示小儿肺炎克雷伯菌对常用抗菌药物皆存有不同程度的耐药性,其中氨苄西林、哌拉西林、头孢唑林、头孢哌酮、头孢呋辛等抗菌药物的耐药性很高。结论小儿肺炎克雷伯菌比较常见,感染率较高,同时对氨苄西林、哌拉西林等抗菌药物耐药性较高,临床应慎重用药。

Objective To analyze the detection rate and their drug resistance of pediatric pneumonia klebsiella bacte- ria, in order to provide the basis for clinical diagnosis and treatment. Methods From January 2012 to December 2013,50 ca- ses of Children with pneumonia were collected as the research object in our hospital, their clinical data were retrospectively an- alyzed. All of the sputum specimens were received bacteriology inspection, and do drug sensitivity test after checking out the klebsiella strain. The detection rate and drug resistance were summary analyzed. Results In 530 cases of infantile pneumonia sputum specimens,232 cases checked out the pathogen, of which 70 strains were klebsiella bacteria （the percentage in the pathogens was 30.17%, the detection rate was 13.21% ） ;Susceptibility test results show that the pediatric pneumonia klebsiel- la bacteria had varying degrees of resistance to commonly used antimicrobial agents, and the resistance to ampicillin, piperacil- lin,cefazolin,cefoperazone,cefuroxime and other antimicrobial agents was high. Conclusion Pediatric pneumonia klebsiella bacteria is common,the infection rate of which is higher, the resistance to ampicillin, piperacillin and other antimicrobial a- gents was high. , so we should be cautious in clinical drug use.