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达比加群酯用药教育 被引量:5

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摘要 华法林是过去半个世纪证实抗凝疗效确切、安全、价格便宜的口服抗凝药,在心脑血管血栓疾病的防治中地位相当重要。但由于其治疗窗比较窄,个体差异大,起效缓慢、药物相互作用常见,需频繁监测凝血时间及国际标准化比值(INR),影响了其在临床实践中的广泛应用[1]。新型口服抗凝药(NOACs)克服了华法林的上述缺点,以其剂量固定,出血风险更低以及药物相互作用小的优势而更受医师及患者的青睐。
出处 《临床合理用药杂志》 2015年第5期92-93,共2页 Chinese Journal of Clinical Rational Drug Use
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同被引文献48

  • 1贺敏,黄仁彬,刘曦.利福平对细胞色素P_(450)超家族及其相关药物的作用[J].中国药房,2006,17(21):1664-1666. 被引量:15
  • 2杨帆,张黎军,蒋小波.达比加群220mg和150mg对膝、髋关节置换术后静脉血栓预防的疗效及安全性评价[J].中华临床医师杂志:电子版,2013,7(1):226-232.
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  • 9SCHULMAN S, KEARON C, KAKKAR AK, et al. Extended use of dabigatran, warfarin, or placebo in venous thromboembolism [J]. N Engl J Med, 2013, 368(8) : 709-718.
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